Food and Drug Administration assessment of Kratom The FDA's assessment of kratom has been characterized by a series of concerns and regulatory actions aimed at addressing potential health risks associated with this botanical substance. In April 2019, the FDA issued a statement emphasizing that kratom had not received approval for any medical use. The agency raised concerns about the safety of kratom products available in the United States and continued to enforce an import alert, which allowed the confiscation of imported kratom supplies. This move underscored the FDA's commitment to ensuring the safety of products containing kratom that enter the...
Does Kratom Show Up on a Drug Test? The primary alkaloids in kratom, mitragynine, and 7-hydroxymitragynine are excreted in urine and can be detected through certain urine drug testing. With an average half-life of about 24 hours, kratom's metabolites can, in theory, be detectable for a period, particularly in heavy, chronic users who regularly consume high doses of the substance. Blood tests, though less commonplace than urine or saliva tests, may also detect kratom use, albeit within a shorter window. As with many substances, the ability to detect kratom in the body varies and can depend on factors such as...
Alkaloids in Kratom Kratom, scientifically known as Mitragyna speciosa, is a tropical tree native to Southeast Asia. One of the most significant elements contributing to its unique biological effects is the presence of alkaloids, particularly Mitragynine. Constituting around 60 percent of the alkaloid content in a typical kratom leaf, Mitragynine interacts with an individual's mu opioid receptors, thereby stimulating an array of responses in the human body. Mitragyna speciosa's complexity extends beyond the mere presence of Mitragynine. The plant encompasses a variety of other alkaloids that jointly contribute to kratom's multifaceted effects. These alkaloids interact synergistically, affecting different receptors in...
Origins of kratom: Geographical, Historical, Cultural Kratom, scientifically known as Mitragyna speciosa, boasts a rich history deeply rooted in Southeast Asia. Its origins can be traced back to countries such as Indonesia and Malaysia, where it flourishes in the lush tropical rainforests. This botanical wonder goes by various native names, including "Ketum" in Malaysia, "Biak-Biak" in Thailand, and "Ithang" in Thailand. The cultural significance of kratom is profound in these regions, with indigenous populations using it for centuries. Traditionally, it has been employed in various rituals and ceremonies, as well as for its potential medicinal properties. Its leaves, the primary...